SKF-86002 is primarily recognized for its role in pharmacological research, particularly in the study of inflammation and immune responses. It functions as a potent and selective inhibitor of 5-lipoxygenase (5-LOX), blocking leukotriene biosynthesis. Additionally, it inhibits cytokine production, specifically targeting the synthesis of interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-α). This makes it a valuable tool in understanding the mechanisms underlying inflammatory diseases such as rheumatoid arthritis and other autoimmune conditions. Researchers utilize SKF-86002 to explore potential therapeutic strategies by modulating inflammatory pathways. Its ability to suppress key pro-inflammatory cytokines and leukotrienes helps in elucidating the complex interactions within the immune system and identifying novel targets for anti-inflammatory drug development.