5-(1,3-dioxolan-2-yl)-2-fluoroaniline
95%
Reagent
Code: #180265
CAS Number
95261-87-3
blur_circular Chemical Specifications
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Molecular Information
Weight
183.18 g/mol
Formula
C₉H₁₀FNO₂
thermostat
Physical Properties
Boiling Point
295.6±40.0 °C(Predicted)
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Storage & Handling
Density
1.294±0.06 g/cm3(Predicted)
Storage
Room temperature, seal, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of fluorinated active pharmaceutical ingredients (APIs) where the fluoroaniline moiety enhances metabolic stability and binding affinity. Its masked aldehyde group (as dioxolane) allows for selective transformations in multi-step syntheses, especially in oncology and central nervous system drug candidates. Also employed in agrochemicals for constructing herbicides and fungicides due to its aromatic fluorine contribution to lipophilicity and bioavailability. Suitable for use in cross-coupling reactions and as a building block in combinatorial chemistry.
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