Ethyl α-chlorophenylacetate
97%
Reagent
Code: #183926
CAS Number
4773-33-5
blur_circular Chemical Specifications
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Molecular Information
Weight
198.6461 g/mol
Formula
C₁₀H₁₁ClO₂
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Registry Numbers
MDL Number
MFCD00013675
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Physical Properties
Boiling Point
258 °C at 760 mmHg
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Storage & Handling
Density
1.162 g/cm3
Storage
2-8°C, stored in inert gas
description Product Description
Used primarily as an intermediate in the synthesis of pharmaceuticals, particularly in the production of non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen and related derivatives. It serves as a key building block due to its reactive α-chloro ester functionality, which allows for nucleophilic substitution and carbon chain elongation. Also employed in the preparation of agrochemicals and fragrances where a phenyl-substituted ester backbone is required. Its versatility in organic synthesis makes it valuable in creating chiral molecules through asymmetric synthesis routes when combined with appropriate catalysts.
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