Cytosine β-D-arabinofuranoside hydrochloride

10mM in DMSO

Reagent Code: #157894
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CAS Number 69-74-9

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 279.68 g/mol
Formula C₉H₁₃N₃O₅·HCl
badge Registry Numbers
MDL Number MFCD00012839
thermostat Physical Properties
Melting Point 197-198 °C(lit.)
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used primarily in the treatment of acute myeloid leukemia and other hematologic cancers, this compound acts as a nucleoside analog that interferes with DNA synthesis. It is incorporated into DNA during the S phase of cell division, leading to chain termination and inhibition of DNA polymerase, which ultimately triggers apoptosis in rapidly dividing cancer cells. It is also used in certain viral infections due to its antiviral activity, particularly against herpesviruses. In research, it serves as a tool to synchronize cell cycles and study DNA repair mechanisms. Its ability to cross the blood-brain barrier makes it useful in treating meningeal leukemia.

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Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿1,850.00

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