α-MaleiMidopropionyl-ω-succiniMidyl-12(ethylene glycol)

95%

Reagent Code: #61957
label
Alias Maleimide-PEG12-NHS Ester; Maleimide-NH-PEG12-CH2CH2COONHS Ester; Maleimide-PEG12-NHS Ester
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CAS Number 756525-92-5

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 865.92 g/mol
Formula C₃₈H₆₃N₃O₁₉
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used in bioconjugation and drug delivery systems, it serves as a linker molecule to connect biomolecules like proteins, peptides, or antibodies with therapeutic agents. Its polyethylene glycol (PEG) segment enhances solubility and reduces immunogenicity, making it suitable for targeted therapies. The maleimide group reacts with thiols, enabling stable conjugation with cysteine residues in proteins, while the succinimidyl ester reacts with amines, facilitating attachment to amino groups. This dual functionality allows precise and efficient coupling in the development of antibody-drug conjugates (ADCs) and other biopharmaceuticals. Its application is particularly valuable in cancer therapy, where it helps deliver cytotoxic drugs specifically to tumor cells, minimizing off-target effects. Additionally, it is used in diagnostic tools for labeling and imaging purposes.

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Test Parameter Specification
Appearance White to off-white or light-yellow solid
Purity 94.5-100
Infrared Spectrum Conforms to Structure
NMR Conforms to Structure

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿30,650.00

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