Cyclic Pifithrin-α Hydrobromide
10mM in DMSO
Reagent
Code: #157811
CAS Number
511296-88-1
blur_circular Chemical Specifications
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Molecular Information
Weight
349.29 g/mol
Formula
C₁₆H₁₆N₂S·HBr
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Registry Numbers
MDL Number
MFCD02683960
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily as a research compound in cellular and molecular biology, this chemical acts as a reversible inhibitor of p53, a tumor suppressor protein involved in cell cycle regulation and apoptosis. By temporarily suppressing p53 activity, it allows scientists to study cell survival mechanisms under stress conditions such as DNA damage. It is particularly useful in experiments aimed at protecting healthy cells from the side effects of chemotherapy and radiation without compromising the treatment’s effectiveness on cancer cells. Additionally, it has been applied in studies related to neuroprotection, ischemia-reperfusion injury, and aging, where controlled modulation of p53 helps clarify its role in disease progression and cell viability.
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