Used as a key intermediate in the synthesis of dexamethasone derivatives, particularly in the development of prodrugs and conjugates for targeted drug delivery. Its carboxylic acid functional group allows for easy coupling to polymers, proteins, or nanoparticles, enabling controlled release and improved pharmacokinetics. Commonly employed in pharmaceutical research to enhance solubility, reduce systemic toxicity, and increase site-specific activity of corticosteroid-based therapies. Also utilized in immunoassay development and as a linker molecule in antibody-drug conjugates (ADCs) for anti-inflammatory and anticancer applications.