Cytosine β-D-arabinofuranoside

10mM in Water

Reagent Code: #157859
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CAS Number 147-94-4

science Other reagents with same CAS 147-94-4

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 243.22 g/mol
Formula C₉H₁₃N₃O₅
badge Registry Numbers
EC Number 205-705-9
MDL Number MFCD00066487
thermostat Physical Properties
Melting Point 214 °C
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used primarily in the treatment of acute myeloid leukemia (AML) and other hematologic malignancies, this compound acts as a chemotherapy agent by interfering with DNA synthesis. It is particularly effective during the S-phase of the cell cycle, where it incorporates into DNA and inhibits chain elongation, leading to apoptosis in rapidly dividing cancer cells. It is also used in the management of meningeal leukemia due to its ability to reach therapeutic concentrations in the central nervous system. In research, it serves as a tool to synchronize cell cycles and study DNA replication and repair mechanisms. Additionally, it has been explored for antiviral applications, particularly against herpesviruses, due to its inhibitory effects on viral DNA polymerase.

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Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿1,590.00

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Cytosine β-D-arabinofuranoside
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Used primarily in the treatment of acute myeloid leukemia (AML) and other hematologic malignancies, this compound acts as a chemotherapy agent by interfering with DNA synthesis. It is particularly effective during the S-phase of the cell cycle, where it incorporates into DNA and inhibits chain elongation, leading to apoptosis in rapidly dividing cancer cells. It is also used in the management of meningeal leukemia due to its ability to reach therapeutic concentrations in the central nervous system. In research, it serves as a tool to synchronize cell cycles and study DNA replication and repair mechanisms. Additionally, it has been explored for antiviral applications, particularly against herpesviruses, due to its inhibitory effects on viral DNA polymerase.
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