DL-α-Lipoic Acid-NHS is widely used in biochemical research for the modification and labeling of proteins, peptides, and other biomolecules. Its NHS ester group enables efficient conjugation with primary amines, making it valuable for creating stable amide bonds in targeted molecular studies. This compound is particularly useful in the development of bioconjugates for applications such as drug delivery systems, where it helps in attaching therapeutic agents to carriers for improved specificity and efficacy. Additionally, it plays a role in the study of oxidative stress and mitochondrial function, as lipoic acid is a key antioxidant. Researchers also utilize it in the preparation of fluorescent or affinity probes for imaging and detection purposes in cellular and molecular biology.