Used as a key intermediate in the synthesis of antidiabetic drugs, particularly in the production of DPP-4 inhibitors like sitagliptin. Its rigid bicyclic structure contributes to high selectivity and potency in enzyme inhibition. Also employed in the development of other pharmaceuticals where a constrained sulfone scaffold enhances metabolic stability and bioavailability. Commonly utilized in medicinal chemistry for structure-activity relationship (SAR) studies involving enzyme inhibitors.