excellent barrier repair, moisturizing, water-locking, anti-allergy, and soothing efficacy. However, due to its water and oil insolubility, ceramide tends to crystallize and precipitate during shelf life, limiting its application in cosmetics. Ceracare™ Oil is a clear oil that contains high concentration of 3 types of ceramides plus Phytosphingosine
Ceracare™ Oil (Clear Oil Ceramide, 2% Minimum Ceramide)
Ceramide has excellent barrier repair, moisturizing, water-locking, anti-allergy, and soothing efficacy. However, due to its water and oil insolubility, ceramide tends to crystallize and precipitate during shelf life, limiting its application in cosmetics. Ceracare™ Oil is a clear oil that contains high concentration of 3 types of ceramides plus Phytosphingosine.
Suitable for any oil based formulation.
Composition:
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Ceramide NP (CERAMIDE NP)
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Ceramide AP (CERAMIDE AP)
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Ceramide EOP (CERAMIDE EOP)
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Phytosphingosine (PHYTOSPHINGOSINE)
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Octyldodecanol (OCTYLDODECANOL)
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Pentylene Glycol (PENTYLENE GLYCOL)
Features and Advantages:
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Multiple ceramides
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Versatile applications
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Engineer/formulator friendly
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High content (2%)
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Mimics ceramides complex ratio in human skin
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Mixes well with GTCC, vegetable oils, etc., without heating
Applications:
Composition Effects:
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Ceramide NP: Rich fatty acids (C18:1/C18:2/C18/C16) to prevent water loss
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Ceramide AP: Promotes exfoliation and metabolism of stratum corneum
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Ceramide EOP: Links lipid bilayers
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Phytosphingosine: Important precursor for ceramides
Application Guidelines:
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Compatible with MCT Oil, wheat germ oil, jojoba seed oil, transparent appearance with no precipitation up to 1.5 months
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Precipitation risk with squalane, silicone oils, and isononyl isononanoate. Use cautiously.
Stability of 5% Ceracare™ Oil in different oil phases (1.5 months):
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Squalane: Turbid, little precipitation
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Isononyl isononanoate: Little precipitation
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MCT Oil: Excellent stability
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Wheat germ oil: Excellent stability
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Jojoba seed oil: Excellent stability
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Dimethicone: Turbidity and precipitation
Efficacy:
Ceramide NP - Efficacy Tests:
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Moisturization via aquaporin proteins
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Soothing (trypsin)
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Cell vitality (fibroblasts)
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Anti-wrinkle firming (elastase inhibition)
Ceramide NP - In Vitro Tests:
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Tested 0.2% ceramide barrier repair cream
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Subjects: 30 individuals (23-59 years old)
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Results: Significant reduction in skin redness, hemoglobin index, and trans-epidermal water loss (TEWL) after 4 weeks
Phytosphingosine - Efficacy:
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Soothing effect by down-regulation of IL-1α gene expression
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Effective oil control (5α-reductase inhibition)
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Antibacterial activity against Propionibacterium acnes
Ceramide AP & EOP:
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Ceramide AP has exfoliating efficacy
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Combined ceramide AP & EOP show positive effects on hydration and TEWL, particularly beneficial for damaged skin
Take-away Tips for Ceracare™ Oil:
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Mimics the ceramides complex ratio in human skin
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Suitable for transparent oil phases
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Stable with no precipitation
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Provides barrier repair, moisturizing, anti-allergy, and soothing effects
Use: The main ingredient in moisturizer products for sensitive skin, dry skin, aging skin, aging skin.
How to mix: Mix in oil phase of the formulation
Utilization rate: 0.1-3%
Product characteristics: transparent liquid
Solubility: Can be dissolved in many oils
Storage: Valid for 24 months, please store in the refrigerator at 6 °C -10 °C Premixed cosmetics should be stored in the refrigerator *Do not freeze, may cause ceramide to deteriorate*
INCI: Ceramide NP (CERAMIDE NP), Ceramide AP (CERAMIDE AP), Ceramide EOP (CERAMIDE EOP), Phytosphingosine (PHYTOSPHINGOSINE), Octyldodecanol (OCTYLDODECANOL), Pentylene Glycol (PENTYLENE GLYCOL)
