2-((Tetrahydro-2H-pyran-2-yl)methoxy)benzoic acid

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Reagent Code: #41190
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CAS Number 1021144-50-2

science Other reagents with same CAS 1021144-50-2

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Weight 236.2637 g/mol
Formula C₁₃H₁₆O₄
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MDL Number MFCD11156614
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This compound, 2-((Tetrahydro-2H-pyran-2-yl)methoxy)benzoic acid, is a tetrahydropyranyl (THP)-protected derivative of salicylic acid (2-hydroxybenzoic acid), where the phenolic hydroxyl group is temporarily shielded by the THP protecting group. It functions as a key intermediate in organic synthesis, enabling selective reactions on the carboxylic acid or other functional groups without interference from the protected hydroxyl. This is particularly valuable in the multistep synthesis of complex molecules, such as pharmaceuticals, natural products, and prodrugs, where precise control over reactivity is crucial. The THP group can be readily cleaved under mild acidic conditions to regenerate the free hydroxyl, making it essential in medicinal chemistry and drug design.

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inventory 100mg
10-20 days ฿4,122.00

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2-((Tetrahydro-2H-pyran-2-yl)methoxy)benzoic acid
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This compound, 2-((Tetrahydro-2H-pyran-2-yl)methoxy)benzoic acid, is a tetrahydropyranyl (THP)-protected derivative of salicylic acid (2-hydroxybenzoic acid), where the phenolic hydroxyl group is temporarily shielded by the THP protecting group. It functions as a key intermediate in organic synthesis, enabling selective reactions on the carboxylic acid or other functional groups without interference from the protected hydroxyl. This is particularly valuable in the multistep synthesis of complex molecules

This compound, 2-((Tetrahydro-2H-pyran-2-yl)methoxy)benzoic acid, is a tetrahydropyranyl (THP)-protected derivative of salicylic acid (2-hydroxybenzoic acid), where the phenolic hydroxyl group is temporarily shielded by the THP protecting group. It functions as a key intermediate in organic synthesis, enabling selective reactions on the carboxylic acid or other functional groups without interference from the protected hydroxyl. This is particularly valuable in the multistep synthesis of complex molecules, such as pharmaceuticals, natural products, and prodrugs, where precise control over reactivity is crucial. The THP group can be readily cleaved under mild acidic conditions to regenerate the free hydroxyl, making it essential in medicinal chemistry and drug design.

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