2-((Tetrahydro-2H-pyran-2-yl)methoxy)benzoic acid
97%
science Other reagents with same CAS 1021144-50-2
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description Product Description
This compound, 2-((Tetrahydro-2H-pyran-2-yl)methoxy)benzoic acid, is a tetrahydropyranyl (THP)-protected derivative of salicylic acid (2-hydroxybenzoic acid), where the phenolic hydroxyl group is temporarily shielded by the THP protecting group. It functions as a key intermediate in organic synthesis, enabling selective reactions on the carboxylic acid or other functional groups without interference from the protected hydroxyl. This is particularly valuable in the multistep synthesis of complex molecules, such as pharmaceuticals, natural products, and prodrugs, where precise control over reactivity is crucial. The THP group can be readily cleaved under mild acidic conditions to regenerate the free hydroxyl, making it essential in medicinal chemistry and drug design.
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