Scutellarein is widely used in pharmaceutical and nutraceutical applications due to its strong biological activities. It exhibits significant anti-inflammatory and antioxidant properties, making it valuable in the development of treatments for chronic inflammatory diseases and oxidative stress-related conditions. It has been studied for its potential in protecting neuronal cells, suggesting a role in therapies for neurodegenerative disorders such as Alzheimer's and Parkinson's disease. In cardiovascular health, scutellarein helps in vasodilation and improving blood flow, which supports its use in managing hypertension and ischemic heart disease. It also shows antiviral activity, particularly against certain respiratory viruses, and is being explored as a supportive agent in antiviral formulations. Due to its ability to inhibit specific enzymes involved in cancer progression, scutellarein is investigated for its anticancer potential, especially in liver, breast, and lung cancer models. Additionally, it is used in cosmetic formulations for its skin-protective effects against UV-induced damage and aging. Its natural origin and low toxicity profile enhance its suitability for use in herbal medicines, dietary supplements, and functional foods aimed at promoting overall health and disease prevention.