Used primarily in dermatological formulations for the treatment of inflammatory skin conditions such as eczema, psoriasis, and allergic dermatitis. It exhibits potent anti-inflammatory, antipruritic (anti-itch), and vasoconstrictive properties, making it effective in reducing redness, swelling, and irritation. Due to its high topical potency and reduced systemic absorption, it is favored in prescription-strength creams and ointments for localized skin disorders. Its metabolite activity also contributes to prolonged therapeutic effects with once-daily application.