N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide
98%
Reagent
Code: #218707
CAS Number
503610-43-3
science Other reagents with same CAS 503610-43-3
blur_circular Chemical Specifications
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Molecular Information
Weight
463.52 g/mol
Formula
C₂₂H₂₆FN₃O₅S
thermostat
Physical Properties
Melting Point
131℃
Boiling Point
695.0±65.0℃(Predicted)
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Storage & Handling
Density
1.387 g/cm3
Storage
-20℃
description Product Description
Widely used in the management of hypercholesterolemia, this compound functions as a potent inhibitor of HMG-CoA reductase, a key enzyme in cholesterol biosynthesis. It effectively lowers low-density lipoprotein (LDL) cholesterol and total cholesterol levels in the bloodstream, reducing the risk of cardiovascular diseases such as atherosclerosis, myocardial infarction, and stroke. Its high bioavailability and long half-life allow for once-daily dosing, improving patient compliance. The compound is particularly effective in patients who do not achieve target cholesterol levels through diet and lifestyle changes alone. It is also used in combination with other lipid-lowering agents for enhanced therapeutic effect. Due to its impact on lipid metabolism, it plays a critical role in both primary and secondary prevention of coronary heart disease.
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